0.01% Hypochlorous Acid in the Treatment of Blepharitis

• Status: Recruiting
• Trial end date: 2023-05-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a multi-center, multidisciplinary, open-label, randomized controlled prospective clinical study.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Eye & ENT Hospital of Fudan University
• Collaborator: ShuGuang Hospital

Criteria

Inclusion Criteria:

1. Age 18 or older.

2. Anterior or mixed (anterior + posterior) blepharitis.

3. Similar clinical condition of both eyes.

4. A negative urine pregnancy test result for women of childbearing potential

5. Normal lid position and closure

6. Ability to understand and provide informed consent to participate in this study

7. Willingness to follow study instructions and likely to complete all required visits.

Exclusion Criteria:

1. Any ocular surface disease other than blepharitis.

2. Known allergy to hypochlorous acid or boric acid.

3. Eye surgery in the last 6 months.

4. History of Stevens-Johnson syndrome or ocular pemphigoid

5. Ocular trauma in the last 6 months.

6. Use of contact lenses in the last 6 months.

7. Pregnancy or lactation.

8. Daily use of makeup on lashes.

9. Any ocular or systemic medication that might affect the ocular microbiota (antibiotics, immunosuppressants, steroids).

10. Pregnant or lactating women

11. Signs of current infection, including fever and current treatment with antibiotics

12. Liver, renal, or hematologic disease

13. The use of any other investigational drug