1% Topical Pimecrolimus Cream for the Treatment of the Rash Associated With ERBITUX
Status:
Terminated
Trial end date:
2014-04-01
Target enrollment:
Participant gender:
Summary
When cancer patients are treated with the drug cetuximab they very often develop a rash.
Usually it appears on their face and back and other parts of the body. The rash looks like
acne and is treated with skin creams or antibiotics most of the time. The rash can become
very painful and cause patients to stop using cetuximab to treat their cancer, even if
cetuximab was helping fight their cancer.
Cetuximab is known to be a good drug to help treat cancer. This study will help us learn
about the rash cetuximab causes so hopefully future patients can finish taking cetuximab for
their cancer. In this study the investigators will use a cream called pimecrolimus (Elidel)
to see if it will help prevent the rash or keep the rash from getting worse. The
investigators also want to see how the rash affects patients and their quality of life.
Participants will be in this study for about four weeks if their rash does not get worse.
They will need to apply the study cream and placebo two times daily and answer quality of
life questionnaires during this study. Participants will also be seen by a dermatologist and
have pictures taken of their rash.