1 Year Study Trav/Brinz QD Fixed Combination Versus COSOPT

• Status: Terminated
• Trial end date: 2009-02-01
• Target enrollment: 0
• Participant gender: All

Summary

Parallel, Multi-Center, Double-masked, Active controlled, three arm study comparing the IOP lowering efficacy and safety over 12 months of morning or evening instillations of Travoprost/Brinzolamide vs. Cosopt dosed in the morning and evening in patients with open-angle glaucoma or ocular hypertension.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alcon Research
• Collaborator: PPD
• Treatments: Brinzolamide; Travoprost

Criteria

Inclusion Criteria:

• IOP at screening visit <18mmHg in at least one eye Mean IOP in same eye (at both eligibility 1 &2 visits)

• 24 and ≤ 36 mmHg at 9:00

• 21 and ≤ 36 mmHg at 11:00 and 16:00

Exclusion Criteria:

• Severe central visual field loss Angle Shaffer grade < 2 C/D ratio > 0.8 (horizontal or vertical measurement)