13-C Urea Breath Test Using BreathID System and PPIs (Proton Pump Inhibitors)

• Status: Completed
• Trial end date: 2009-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Approximately 200 patients with suspected H.pylori will be tested with a 13C-Urea Breath Test (UBT) to ascertain H.pylori positive. 100 H.Pylori positive patients will tested before and after prescribed with one of the four selected Proton Pump Inhibitors (PPIs); 25 patients in each arm. This will provide information on the influence of PPIs on the UBT (Urea Breath Test). The aim of the trial is to observe the effect of different PPIs on the breath test and choose the optimal protocol of when to stop PPI. The hypothesis is that there will be a minimal effect on the UBT while using selected PPIs.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Exalenz Bioscience LTD.
• Collaborator: Rabin Medical Center
• Treatments: Dexlansoprazole; Esomeprazole; Lansoprazole; Omeprazole; Pantoprazole; Proton Pump Inhibitors

Criteria

Inclusion Criteria:

• Adults with H.pylori infection.

Exclusion Criteria:

• Pregnancy,

• Nursing,

• Antibiotic, bismuth or PPI treatment 2 weeks prior to trial,

• Known sensitivity to Urea or citrica.