16-week Comparative Effectiveness Trial of Lamotrigine vs. Fluoxetine for Bipolar Depression
Status:
Terminated
Trial end date:
2018-05-23
Target enrollment:
Participant gender:
Summary
The FLAME Study is a 16-week clinical trial to study treatment with lamotrigine or fluoxetine
in bipolar I, II and bipolar schizoaffective depressed adults. The purpose of the trial is to
have a better understanding of whether individuals with a particular gene type and other
inherited biological markers will have a good response to fluoxetine or lamotrigine, or
alternatively, would be more likely to have side effects to this medication.
Phase:
Phase 4
Details
Lead Sponsor:
Mayo Clinic
Collaborators:
J Willard and Alice S. Marriott Foundation Marriott Family and Foundation