24 Vs 48 Hours of Cefazolin or Cefuroxime as Prophylaxis

• Status: Recruiting
• Trial end date: 2022-01-31
• Target enrollment: 0
• Participant gender: All

Summary

A randomized control trial studying the effect of prophylactic antibiotics to reduce surgical site infections following cardiac surgery in adults using 1st generation cephalosporin (Cefazolin) or 2nd generation cephalosporin (Cefuroxime).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Saud Al Babtain Cardiac Center
• Treatments: Cefazolin; Cefuroxime; Cefuroxime axetil; Cephalosporins

Criteria

Inclusion Criteria:

• Ability to provide informed consent

• Planned to undergo a cardiac surgical procedure

Exclusion Criteria:

• Patients on antibiotics on the day of surgery or those who received any within 7 days for any reason

• Patients taken to operating room as salvage

• Patients who are allergic to either cefuroxime or cefazolin

• Patients for LVAD or ECMO

• Patients who are known MRSA carriers

• Patients receiving steroid therapy