24-hour Control of Intraocular Pressure (IOP) in Ocular Hypertension
Status:
Completed
Trial end date:
2004-02-01
Target enrollment:
Participant gender:
Summary
This study was designed to compare the 24-hour efficacy on intra ocular pressure (IOP) of
drugs acting either on aqueous humor production ("inflow drugs") or on aqueous humor outflow
("outflow drugs") in human eyes affected by ocular hypertension and virgin to treatment. The
enrolled patients will be exposed, in a cross-over design, to n = 2 aqueous suppressants and
n= 3 uveoscleral outflow enhancers, and 24 hr IOP will be measured. It is hypothesised that
outflow drugs may offer a better and more stable control of IOP through the 24 hours.