24-hr Intraocular Pressure Control With Dorzolamide/Timolol vs the Brimonidine/Timolol Fixed Combination
Status:
Completed
Trial end date:
2009-09-01
Target enrollment:
Participant gender:
Summary
The proposed study will compare for the first time the quality of 24-hour IOP control with
Brimonidine/Timolol fixed combination (BTFC) versus Dorzolamide/Timolol fixed combination
(DTFC) after a run-in period of 2 months with timolol. This crossover comparison may
determine the real efficacy of the two fixed combinations and the design of the proposed
study may explain for the first time why the 24-hour IOP reduction provided by BTFC is less
than might be anticipated.