68-Ga-FAPI PET Imaging in Malignancy

• Status: Not yet recruiting
• Trial end date: 2022-12-14
• Target enrollment: 0
• Participant gender: All

Summary

This feasibility trial studies the use of gallium-68 (68Ga)-FAPI as the imaging agent for positron emission tomography (PET)/computed tomography (CT), collectively PET/CT, in patients with various cancers. PET uses a radioactive substance called 68Ga-FAPI, which attaches to cancer activated fibroblasts. The PET scanner takes pictures that capture where the radioactive drug is "lighting up" and attaching to tumor cells, which may help doctors recognize differences between tumor and healthy tissue. CT uses X-rays to make a picture of areas inside the body. Using 68Ga-FAPI in diagnostic procedures, such as PET/CT, may allow doctors to identify smaller tumors than standard imaging.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Stanford University

Criteria

Inclusion Criteria:

• Patient with current malignancy confirmed via pathology or imaging

• Patient must be > 18 years old

• Patient must be willing and able to provide written informed consent for the trial

• Patient of reproductive potential will have a pregnancy test

Exclusion Criteria:

• Pregnant or breastfeeding