A Clinical Study of a Natural Remedy for Rheumatoid Arthritis vs. Commonly Used Conventional Medications

• Status: Completed
• Trial end date: 2012-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the efficacy and safety of a combined therapy for rheumatoid arthritis (RA). The combined therapy contained paeoniflorin (Brand name: Pafulin), which has anti-inflammation properties, and Cervus and Cucumis polypeptide injection (Brand name: Songmeile), which has bone healing, pain relieving, and anti-inflammation properties. The hypothesis is that this remedy, which has long been used by the world's largest RA community, is effective and safe when tested by modern clinical standards and criteria.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Minnesota; University of Minnesota - Clinical and Translational Science Institute
• Treatments: Leflunomide; Methotrexate; Peoniflorin

Criteria

Inclusion Criteria:

• age of 18 years or older

• active RA, defined by at least 8 swollen joints and at least 10 tender joints (excluding distal interphalangeal joints)

• an erythrocyte sedimentation rate (ESR) of at least 28 mm per hour

• the 1987 revised American College of Rheumatology (ACR) criteria for diagnosis of RA for at least 6 months

• not use of NSAIDs within two weeks

• agreement to participate in this study.

Exclusion Criteria:

• poor compliance

• severe medical conditions

• abnormalities in liver, or kidney function, or in haematological parameters,

• pregnancy or breast feeding