Overview

A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients

Status:
Completed
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine in a randomized, placebo-controlled, phase II trial if the combination of sulindac and erlotinib causes a significant regression of duodenal and colorectal adenomas in familial adenomatous polyposis (FAP) and attenuated FAP (AFAP) patients.
Phase:
Phase 2
Details
Lead Sponsor:
University of Utah
Collaborator:
National Cancer Institute (NCI)
Treatments:
Erlotinib Hydrochloride
Sulindac