A Clinical Trial of a Radiation Sensitizer in Radiochemotherapy for Thoracic Esophageal Squamous Carcinoma

• Status: Unknown status
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This multicentered clinical trial is going to find out the radio-sensitization action of sodium glycididazole in radiochemotherapy for esophageal cancer.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shandong Luye Pharmaceutical Co., Ltd.

Criteria

Inclusion Criteria:

• written informed consent

• photographically and histologically proven thoracic esophageal squamous carcinoma

• stages 2a-3, and stage 4 with only supraclavicular lymph nodes metastasis defined by AJCC(2002)

• radiochemotherapy indication

• measurable tumor

• adequate hematologic, hepatic and renal function

• Karnofsky performance status ≥70

• age more than 18years and less than 70 years

Exclusion Criteria:

• pregnancy and lactation

• significant neurologic disease

• severe liver and renal malfunction,and Significant medical illness

• previous chemotherapy, radiotherapy or immunotherapy

• esophagus hemorrhage and esophagus perforation features