A Clinical Trial to Compare Topical Agents in Adults With Mild to Moderate Atopic Dermatitis (AD)

• Status: Completed
• Trial end date: 2015-07-01
• Target enrollment: 0
• Participant gender: All

Summary

An Explorative Clinical Trial to Evaluate an Intra Patient Comparison Design of Topical Agents in Adults with Mild to Moderate Atopic Dermatitis.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: LEO Pharma
• Treatments: Betamethasone; Betamethasone benzoate; Betamethasone sodium phosphate; Betamethasone Valerate; Betamethasone-17,21-dipropionate; Clobetasol; Emollients; Pimecrolimus; Tacrolimus

Criteria

Inclusion Criteria:

• Subject with mild to moderate AD

• Four comparable TAs

• TSS of at least 5 on all TAs

• Difference in TSS not greater than 2 between the TAs

• Sign score erythema ≥ 2 between the TAs

• TAs should be at least 2 cm apart

Exclusion Criteria:

• Investigator's opinion

• Fitzpatrick skin type >5

• Topical (i.e. on the TAs) treatment with prohibited medications

• Systemic treatment with prohibited medications

• Phototherapy within prohibited timeframe

• Use of emollients within prohibited timeframe