A Comparative Study of Intrathecal Magnesium Sulphate & Midazolam With Epidural Ropivacaine for Caesarean Patients

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study compares whether addition of Magnesium or Midazolam intrathecally to epidurally administered isobaric Ropivacaine improves the quality of blockade, haemodynamics and duration of analgesia post-operatively. 25 parturients were given intrathecal Magnesium and rest of the 25 parturients were given intrathecal Midazolam combined with 0.75% Ropivacaine via epidural route.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Rangaraya Medical College
• Treatments: Magnesium Sulfate; Midazolam; Ropivacaine

Criteria

Inclusion Criteria:

• 50 pregnant women

• ASA-I and II parturients

• Weight 50-80 kgs

• Pre-eclampsia

Exclusion Criteria:

• Thrombocytopenia

• HELLP syndrome

• Parturients on magnesium therapy

• Foetal distress

• Parturients on benzodiazepine therapy

• Patient refusal

• Contraindications to regional anaesthesia