A Comparative Study of Prophylactic Anticoagulation in Meningioma Surgery
Status:
Completed
Trial end date:
2015-10-01
Target enrollment:
Participant gender:
Summary
The aim of the study is to compare different strategies for prevention of venous
thromboembolism related to intracranial meningioma surgery. The investigators identified
three hospitals where two have a very restrictive approach with respect to anticoagulant
therapy while at the third hospital the use of anticoagulation the day before surgery was
initiated as routine prophylaxis.
Based on this "natural experiment" it will be explored whether the use of anticoagulant
prophylaxis is associated with reduced risk of venous thromboembolism and/or associated with
increased risk of postoperative hemorrhage as compared to the 2 cohorts where this
intervention were absent.
Details
Lead Sponsor:
St. Olavs Hospital
Collaborators:
Karolinska University Hospital Norwegian University of Science and Technology University Hospital of North Norway