A Comparison of Bupivacaine and 2-chloroprocaine for Spinal Anesthesia

• Status: Completed
• Trial end date: 2009-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the efficacity and the readiness for discharge between two local anesthetics, bupivacaine and 2-chloroprocaine, used for spinal anesthesia.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Université de Montréal
• Collaborator: Centre hospitalier de l'Université de Montréal (CHUM)
• Treatments: Anesthetics; Bupivacaine; Chloroprocaine; Procaine

Criteria

Inclusion Criteria:

• patients aged 18 years and older

• urologic elective ambulatory procedure. For example:cystoscopy, circumcision,transurethral bladder tumor resection, varicocele and hydrocele surgery

• gynecologic elective ambulatory procedure. For example: hysteroscopy, vulvar ou vaginal biopsy

• general surgery elective ambulatory procedure. For example:inguinal herniorraphy, short ano-rectal procedure

Exclusion Criteria:

• INR > 1,3

• platelet < 75 000

• concomitant drugs: clopidogrel (last dose < 7 days), iv heparin, low molecular weight heparin (last dose < 24 hours)

• neurologic disease: spinal stenosis, symptomatic lumbar herniated disc, multiple sclerosis

• liquid restriction (cardiac or renal insufficiency)

• allergy or intolerance to chloroprocaine, bupivacaine or PABA

• atypical plasma cholinesterase or deficiency