A Comparison of Bupivacaine and Ketorolac for Postoperative Analgesia After Iliac Crest Bone Harvesting

• Status: Completed
• Trial end date: 2008-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The efficacy of three postoperative pain management regimens will be compared in patients undergoing Lefort I osteotomy or alveolar cleft repair with Iliac crest bone grafts (ICBG) to determine the best way of managing postoperative pain.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Hospital for Sick Children
• Treatments: Bupivacaine; Ketorolac; Ketorolac Tromethamine

Criteria

Inclusion Criteria:

• Alveolar bone graft patients age 10-13 years of age

• Lefort I osteotomy patients needing ICBG age 14 to 20 years

• able to operate a patient-controlled analgesia (PCA) device

Exclusion Criteria:

• Allergy, sensitivity or contraindication to any non-steroidal anti-inflammatory drugs

• Allergy, sensitivity or contraindication to morphine

• History of gastric ulcer or bleeding diathesis