A Comparison of Crystalloid Alone Versus Crystalloid Plus Colloid in Shock Resuscitation
Status:
Unknown status
Trial end date:
2018-11-01
Target enrollment:
Participant gender:
Summary
Fluid resuscitation is the most effective treatment of shock. Isotonic crystalloid solution
is the current recommended initial fluid resuscitation. However, this kind of fluid has high
volume of distribution and may require large volume administration before achieve therapeutic
goal of shock reversal. There are rising concern about the delay in shock reversal and
adverse consequences of large amount volume of fluid therapy. Colloid fluid have been used as
the alternate fluid resuscitation, aiming to limit the volume of fluid resuscitation and
promote shock reversal. Whether colloid infusion can improve shock reversal rate and decrease
complication associated with fluid resuscitation, had inconclusive information.