A Comparison of Gabapentin and Ketamine in Acute and Chronic Pain After Inguinal Hernia Repair

• Status: Recruiting
• Trial end date: 2021-02-02
• Target enrollment: 60
• Participant gender: All

Summary

Patients were randomized into two groups: Group Gabapentine ( G group) received 600 mg of Gabapentin (two tablets) two hours prior to surgery and saline solution before induction of spinal anesthesia and group Ketamine ( K group) received two placebo tablets and an injection of ketamine at a dosage of 0.15 mg/Kg before induction of spinal anesthesia.. During the surgery, blood pressure and heart rate were monitored. Postoperative analgesia was provided by a PCA morphine. Acute postoperative pain was assessed by a visual analog scale. The incidence of postoperative neuropathic pain was detected by the DN4 questionnaire after one and three months of surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Tunis El Manar
• Treatments: Gabapentin; Ketamine

Criteria

Inclusion Criteria:

• ASA I and II

• Inguinal Hernia Repair in non emergent conditions

Exclusion Criteria:

• Patients with significant cardiovascular central nervous system disease, renal or liver failure could not operate the PCA device