A Comparison of Oral Misoprostol and Vaginal Misoprostol for Cervical Ripening and Induction of Labor
Status:
Recruiting
Trial end date:
2022-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to study if misoprostol administered orally is at least as
effective as misoprostol administered vaginally for cervical ripening and the induction of
labor. The main purpose is to show that oral misoprostol administration is non-inferior to
vaginal misoprostol administration with respect to the time interval from misoprostol
administration to onset of active phase of labor. The study is a non-inferiority, prospective
randomized controlled trial comparing oral misoprostol given as 25 mcg every 2 hours versus
vaginal misoprostol given as 25 mcg every 4 hours.