A Comparison of PR Oxycodone/Naloxone and PR Oxycodone After Cardiac Surgery

• Status: Completed
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to describe the effects of oxycodone/naloxone combination in comparison to oxycodone for the treatment of postoperative pain in patients undergoing cardiac surgery. The hypothesis is that the duration of opioid-induced bowel dysfunction and the need of laxatives will decrease.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kati Järvelä
• Treatments: Naloxone; Oxycodone

Criteria

Inclusion Criteria:

• Adult cardiac surgery patient

Exclusion Criteria:

• Preoperative continuous use of laxatives

• Known anatomic or functional gastrointestinal disorder