A Comparison of Patch vs. Pill Estrogen Therapy on Testosterone Levels and Thyroid Tests in Menopausal Women

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

This study compares the effects of 12 weeks of treatment with transdermal versus oral estrogen therapy on testsoterone levels and thyroid tests in healthy, naturally menopausal women.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Watson Pharmaceuticals
• Collaborator: Massachusetts General Hospital
• Treatments: Androgens; Estrogens; Estrogens, Conjugated (USP); Testosterone

Criteria

Inclusion Criteria:

• Healthy

• Naturally menopausal women

• Aged 42-70 years

• Currently using combination estrogen-progestin replacement therapy

Exclusion Criteria:

• Women with contraindications to HRT use, including:Unexplained vaginal bleeding, liver disease, breast or endometrial cancer, venous thromboembolic events

• Thyroid disease

• Adrenal disease