A Comparison of Two Initial Dosing Formulas

• Status: Completed
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will evaluate two methods of starting basal insulin to see which method may achieve a faster-to-goal titration.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Diabetes Care Center
• Treatments: Insulin; Insulin Detemir; Insulin, Globin Zinc

Criteria

Inclusion Criteria:

1. Type 2 diabetes

2. Age 18 years and above

3. Concurrently on ± sulfonylureas ± thiazolidinedione ± DDP IV inhibitors ± metformin ± glinides

4. A1c ≥ 7.0% but ≤ 10%

5. Capable of self monitoring glucose ≥4/day

6. Previously compliant with clinical recommendations

7. Fasting blood glucose ≥ 150 mg/dl

8. BMI ≤ 45 kg/m2

Exclusion Criteria:

1. Urinary ketosis

2. Currently or expected alteration in insulin sensitivity such as major surgery, infection, renal failure (creatinine >1.5 mg/dl), glucocorticoid treatment, recent (within 2 weeks) serious hypoglycaemic episode (requires assistant of another)

3. Currently participating in another clinical trial

4. Known or suspected allergy to insulin determir

5. Using insulin

6. Pregnancy or nursing or the intention of becoming pregnant or not using adequate

7. Significant liver or heart failure.