A Dose Evaluation Study of the Effect of Plug Placement on the Efficacy and Safety of the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma

• Status: Completed
• Trial end date: 2012-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the effect of plug placement on the efficacy, safety and duration of effect of the L-PPDS (latanoprost punctal plug delivery system).

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mati Therapeutics Inc.
• Treatments: Latanoprost

Criteria

Inclusion Criteria:

• Male or female at least 18 years old

• Diagnosis of bilateral open angle glaucoma or ocular hypertension

• Unmedicated IOP must be ≥22mm Hg

Exclusion Criteria:

• Any significant vision loss in the last year

• No contact lens use for the length of the study

• Abnormal eye lids, eye infection or diseases to the eye

• Recent eye surgery

• Uncontrolled medical conditions