A Dose Finding Study of Remifentanil and Propofol for Lumbar Punctures in Children

• Status: Completed
• Trial end date: 2008-01-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will examine whether the combination of two anaesthetic medications, propofol and remifentanil, is suitable for short duration surgical procedures, providing a shorter recovery time and fewer side effects than either drug used alone.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Hospital for Sick Children
• Treatments: Propofol; Remifentanil

Criteria

Inclusion Criteria:

• Clinical diagnosis of a hemato-oncological disorder

• Scheduled to undergo a lumbar puncture

• Aged 4-11 years

• Male or female

• Unpremedicated

• Willing and able to provide informed consent (or informed consent by parents)

Exclusion Criteria:

• Children who are known or suspected to be difficult to ventilate by face mask

• Children who are deemed medically unfit to receive either of the two study medications

• Children who are obese (weight for height > 95th percentile,

• Children who do not have an indwelling intravenous line