A Double-Blind, Placebo-Controlled Study Examining the Use of Topiramate in the Treatment of Cluster Headache
Status:
Terminated
Trial end date:
2006-06-01
Target enrollment:
Participant gender:
Summary
Topiramate is a medication that has been approved by the Food and Drug Administration (FDA)
for the treatment of patients with seizures. The trade name for this drug is Topamax®.
Topiramate has not been approved by the FDA for the treatment of cluster headache and is
experimental for the purposes of this research study. If a subject participates in this
study, he/she will increase his/her dose of topiramate rapidly in the first few weeks to try
to stop the cluster attacks and then will continue on a maintenance dose of topiramate in
order to determine if it can prevent attacks from occurring during that cluster period. We
believe that this will lead not only to a faster but a more complete remission of the cluster
period.