A Double-blind, Randomized, Controlled Trial of Quetiapine Versus Haloperidol for the Treatment of Delirium

• Status: Terminated
• Trial end date: 2012-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether quetiapine, and haloperidol are effective and safe in the treatment psychiatric symptoms in patients with delirium.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chiang Mai University
• Treatments: Haloperidol; Haloperidol decanoate; Quetiapine Fumarate

Criteria

Inclusion Criteria:

• Male or female age 18 -75 years

• Was admitted in Maharaj Nakhon Chiang Mai hospital

• Was diagnosed by the diagnostic criteria for DSM-IV-TR delirium due to a general medical condition or delirium due to multiple etiologies

• Delirious state (delirium) of the patients was confirmed by using name-assess confusion assessment method (CAM) and assessment of severity with delirium rating scale-revised-98 (DRS-R-98)

• Have a written consent from the legal representatives

Exclusion Criteria:

• Was diagnosed substance withdrawal delirium

• Having a history drug allergy either from quetiapine or haloperidol

• Female patients who are pregnant or breastfeeding

• No written consent from the legal representatives

• Received other anti-psychotic drug before attend the study

• Being ill with renal or hepatic failure