A Drug-Drug Interaction Study Between Fenofibric Acid and Efavirenz
Status:
Completed
Trial end date:
2012-01-01
Target enrollment:
Participant gender:
Summary
Efavirenz is predominantly metabolized by cytochrome P450 (CYP) 2B6. Fenofibric Acid is an
inhibitor of CYP2B6. This study will evaluate the effect of multiple doses of fenofibric acid
at steady-state on the pharmacokinetics of single-dose efavirenz in healthy adult subjects.