A Drug-drug Interaction Trial of Loperamide Pharmacokinetics Effect on Pyrotinib Maleate
Status:
Not yet recruiting
Trial end date:
2021-10-01
Target enrollment:
Participant gender:
Summary
The primary objective of the study was to assess the effect of repeated oral doses of
Loperamide on the pharmacokinetic profile of a single dose of Pyrotinib Maleate.
The secondary objective of the study was to assess the safety of Pyrotinib Maleate given
alone versus Fluzoparib coadministered with Loperamide.