A Drug to Drug Interaction Study of Sotagliflozin With Midazolam and Metoprolol
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
Primary Objective:
To assess the effect of repeated once-daily oral doses of sotagliflozin on CYP2D6 and CYP3A
activities using a CYP probe cocktail of metoprolol and midazolam.
Secondary Objective:
To assess the clinical and laboratory safety of sotagliflozin coadministered with the
cocktail probes as compared to that of cocktail probes alone.