Overview
A Feasibility Study of Smoking Cessation Program in Radiation Oncology
Status:
Completed
Completed
Trial end date:
2007-04-01
2007-04-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
To test the feasibility of an intensive behavioral and pharmacologic tobacco cessation program for radiation oncology patients and their families/companions.Phase:
N/AAccepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Indiana University School of MedicineCollaborator:
Walther Cancer InstituteTreatments:
BupropionCriteria
Inclusion Criteria:- Eligibility for Radiotherapy Patients
- age 18 years or older
- receiving three weeks or more of external beam radiotherapy
- report smoking one or more cigarettes in the past 30 days or self-identify as a smoker
- Cancer Stage:
- Stage I-III
- IVa Head and Neck Malignancy is allowed
- Stage I-IV breast, prostate, testis or lymphoma also allowed
- at least one year life expectancy
- have given written informed consent
- KPS 70-100
Eligibility for Family/Companions of Radiotherapy Patients (Note: Family members/companions
are eligible for this protocol regardless of whether the index radiotherapy patient is
eligible or willing to participate.)
- age 18 years or older
- at least one year life expectancy
- radiotherapy patient is receiving three weeks or more of external beam radiotherapy
- Person is committed to bringing/accompanying the patient to radiotherapy at least
three days per week.
- report smoking one or more cigarettes in the past 30 days or self-identify as a smoker
- Family member/companion of patients under radiotherapy treatment for any stage of
cancer
- have given written informed consent
- KPS 70-100
Exclusion Criteria:
- Exclusion Criteria for both Radiotherapy Patients and their Families/Companions
- serious or unstable cardiac, renal, hypertensive, pulmonary, endocrine, or neurologic
disorders, as assessed by the study-site physician
- a current diagnosis of major depressive episode or a history of panic disorder,
psychosis, bipolar disorder, or eating disorders
- pregnancy or lactation
- any history of allergy/intolerance or adverse reaction to bupropion
- history of seizure disorder, bulimia or anorexia nervosa
- use of an MAOi within 14 days
- current use of another antidepressant
- abrupt discontinuation of alcohol or sedatives
- unwilling/unable to meet with the behavioral interventionalist for 20 minutes, at
least 3 days per week during the course of radiotherapy