Overview

A Feasibility Study of Smoking Cessation Program in Radiation Oncology

Status:
Completed
Trial end date:
2007-04-01
Target enrollment:
0
Participant gender:
All
Summary
To test the feasibility of an intensive behavioral and pharmacologic tobacco cessation program for radiation oncology patients and their families/companions.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Indiana University School of Medicine
Collaborator:
Walther Cancer Institute
Treatments:
Bupropion
Criteria
Inclusion Criteria:

- Eligibility for Radiotherapy Patients

- age 18 years or older

- receiving three weeks or more of external beam radiotherapy

- report smoking one or more cigarettes in the past 30 days or self-identify as a smoker

- Cancer Stage:

- Stage I-III

- IVa Head and Neck Malignancy is allowed

- Stage I-IV breast, prostate, testis or lymphoma also allowed

- at least one year life expectancy

- have given written informed consent

- KPS 70-100

Eligibility for Family/Companions of Radiotherapy Patients (Note: Family members/companions
are eligible for this protocol regardless of whether the index radiotherapy patient is
eligible or willing to participate.)

- age 18 years or older

- at least one year life expectancy

- radiotherapy patient is receiving three weeks or more of external beam radiotherapy

- Person is committed to bringing/accompanying the patient to radiotherapy at least
three days per week.

- report smoking one or more cigarettes in the past 30 days or self-identify as a smoker

- Family member/companion of patients under radiotherapy treatment for any stage of
cancer

- have given written informed consent

- KPS 70-100

Exclusion Criteria:

- Exclusion Criteria for both Radiotherapy Patients and their Families/Companions

- serious or unstable cardiac, renal, hypertensive, pulmonary, endocrine, or neurologic
disorders, as assessed by the study-site physician

- a current diagnosis of major depressive episode or a history of panic disorder,
psychosis, bipolar disorder, or eating disorders

- pregnancy or lactation

- any history of allergy/intolerance or adverse reaction to bupropion

- history of seizure disorder, bulimia or anorexia nervosa

- use of an MAOi within 14 days

- current use of another antidepressant

- abrupt discontinuation of alcohol or sedatives

- unwilling/unable to meet with the behavioral interventionalist for 20 minutes, at
least 3 days per week during the course of radiotherapy