Overview

A Medication Trial Combined With Behavior Therapy for Individuals With Obsessive-compulsive Disorder

Status:
Completed
Trial end date:
2007-12-01
Target enrollment:
0
Participant gender:
All
Summary
This study examines the efficacy of the medication D-Cycloserine in the reduction of obsessions and compulsions in individuals with obsessive-compulsive disorder (OCD). All study participants will receive Exposure and Response Prevention, a common form of behavior therapy for individuals with OCD. Half (50%) of the participants will be randomly assigned to the placebo condition and the other half (50%) will be randomly assigned to receive D-Cycloserine. Because all participants will receive 10 sessions of behavior therapy, all participants are expected to improve from this treatment.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Massachusetts General Hospital
Treatments:
Cycloserine
Criteria
Inclusion Criteria:

- Meets diagnosis for obsessive-compulsive disorder

Exclusion Criteria:

- History of psychotic disorders

- History of neurological disorders

- History of bipolar disorders