A Multicenter Open-label Clinical Study on the Prevention of Premature Ovarian Failure After HSCT
Status:
Not yet recruiting
Trial end date:
2025-10-31
Target enrollment:
Participant gender:
Summary
HSCT is an effective method to cure hematologic malignancies. However, the reproductive
system is prone to be damaged during radiotherapy and chemotherapy before transplantation,
leading to ovarian failure, followed by infertility and premature ovarian failure (POF),
which seriously affect the long-term quality of life of patients. This clinical trial aimed
to observe the effect of Gonadotropin-releasing hormone analogues (GnRHa) on ovarian function
in women of reproductive age after HSCT, so as to provide clinical evidence for whether GnRHa
should be used for the prevention of POF.
Phase:
N/A
Details
Lead Sponsor:
First Affiliated Hospital Xi'an Jiaotong University