A Multicenter Study to Evaluate a Risk-adapted Strategy for Treatment of Extra Cranial Non Seminomateous Malignant Germ Cell Tumour in Children and Adolescent

• Status: Active, not recruiting
• Trial end date: 2024-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The main objective is to assess the benefit-risk ratio of a risk-adapted strategy for treatment of extra cranial NSMGCT in children and adolescent.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre Leon Berard
• Treatments: Bleomycin; Cisplatin; Ifosfamide; Isophosphamide mustard; Vinblastine

Criteria

Inclusion Criteria:

• Extra cranial non seminomateous malignant germ cell tumour (NSMGCT) except pure immature teratoma.

• Age ≤ 18 years.

• Affiliation with a social security scheme.

• Signed informed consent by parents

• Effective contraception during the study if relevant .

Exclusion Criteria:

• Previous chemotherapy

• Contraindications to study treatments

• Patient who cannot follow medical surveillance due to geographical, social, or psychological reasons

• Pregnant and breast feeding women