A Multimodality Image-guided System for Peripheral Lung Cancer Diagnosis and Therapy

• Status: Terminated
• Trial end date: 2019-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this clinical research study is to test the use of a minimally invasive multimodality image-guided (MIMIG) intervention system used for performing a lung biopsy. The safety of the MIMIG intervention system will also be studied.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Stephen T. Wong, PhD; The Methodist Hospital Research Institute
• Collaborators: M.D. Anderson Cancer Center; The Methodist Hospital System

Criteria

Inclusion Criteria:

• Adult (age ≥ 18 years) subjects with peripheral lung lesions that are <1.5 cm in size who are planning to undergo percutaneous image guided lung biopsy as part of their routine medical care.

• 2. Ability to understand and willingness to sign Informed Consent Document (ICD)

Exclusion Criteria:

• Age less than 18 years.

• Pregnant or nursing females.

• Known allergy to iodine or intravenous contrast agent.

• Known allergy or anaphylactic reaction to indocyanine green (ICG).

• Patients with renal dysfunction (GFR <60) or patients on dialysis

• Patients with liver dysfunction: total bilirubin > 2.5 mg/dl; albumin < 2.5 mg/dl; alanine aminotransferase (ALT), aspartate aminotransferase (AST) > 5 times upper limits of normal

• Uncorrectable coagulopathy prohibiting biopsy. (INR > 1.5 and/ or platelets < 50,000)