A Multiple Ascending Dose Study of RO4998452 in Patients With Type 2 Diabetes Mellitus.
Status:
Completed
Trial end date:
2009-03-01
Target enrollment:
Participant gender:
Summary
This study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of
multiple ascending doses of RO4998452 compared to placebo in patients with type 2 diabetes
mellitus. Successive cohorts of patients will be randomized to receive either active drug, at
escalating doses, or placebo. The anticipated time on study treatment is <3 months, and the
target sample size is <100 individuals.