A Neuroimaging and Epigenetic Investigation of Antidepressants in Depression
Status:
Completed
Trial end date:
2011-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is:
1. to find out the structural or functional effects of selective serotonin reuptake
inhibitors (SSRI) in major depressive disorder (MDD);
2. find special abnormalities in depression secondary to other disease, e.g., autoimmune
disease like systemic lupus erythematosus (SLE).
3. find the relationship between the efficacy of antidepressant and the change of
neuroimaging in MDD
4. to find possible predispose to MDD
5. to explore the DNA methylation status in depression;