A Norwegian Trial Comparing Treatment Strategies for Carpal Tunnel Syndrome
Status:
Not yet recruiting
Trial end date:
2025-12-01
Target enrollment:
Participant gender:
Summary
Carpal tunnel syndrome (CTS) causes numbness and pain in the hand and arm, and is an
important cause of work absence and disability. The aim of the NOR-CACTUS Trial is to compare
outcomes of a treatment strategy where the initial treatment is up to two ultrasound-guided
corticosteroid injections, followed by scheduled clinical assessment of treatment effect, and
subsequent surgery if needed, to a treatment strategy where surgery is the first-line
treatment. Participants will be randomized to one of the treatment strategies, and followed
up for two years after start of the study intervention. Outcomes will include
patient-reported, clinical, functional and neurophysiological measures, and health-economic
aspects. The hypothesis of the study is that there is no difference between the two treatment
groups in the percentage of patients with a satisfactory symptom relief (treatment success)
one year after the initial therapeutic intervention.
Phase:
Phase 4
Details
Lead Sponsor:
Diakonhjemmet Hospital
Collaborators:
Martina Hansen's Hospital Oslo University Hospital South-Eastern Norway Regional Health Authority