A Novel Anti-Obesity Drug Combination as a Pharmacotherapy for Cocaine Dependence
Status:
Completed
Trial end date:
2018-06-01
Target enrollment:
Participant gender:
Summary
The research proposed in this application will determine the initial efficacy, safety and
tolerability of a novel drug combination, bupropion and naltrexone, as a pharmacotherapy for
cocaine dependence. A rigorous, inpatient human laboratory study will be conducted. The
proposed study is innovative and important because it will provide the impetus for the
conduct of double blind, placebo-controlled trials to further demonstrate the efficacy of
bupropion-naltrexone combinations for managing cocaine dependence.