A Novel Mouthwash Formulation CTP/BNZ With Mucus Adhesive Polymer
Status:
Completed
Trial end date:
2018-03-30
Target enrollment:
Participant gender:
Summary
The purpose of the study is to evaluate the local tolerability and the systemic availability
of benzydamine, if any, after single and multiple dose treatment with the test formulation
containing cetylpyridinium chloride 0.05% + benzydamine hydrochloride 0.15% + mucoadhesive
polymer and with the reference formulation Tantum Verde Bocca containing cetylpyridinium
chloride 0.05% + benzydamine hydrochloride 0.15% to healthy subjects , under fasting
conditions, in two consecutive study periods.