A Pharmacokinetic Study on Co-administration of Tamiflu (Oseltamivir) and Rimantadine in Healthy Volunteers
Status:
Completed
Trial end date:
2010-02-01
Target enrollment:
Participant gender:
Summary
This open label, randomized, three-period crossover study will evaluate the effect of
co-administration of Tamiflu (oseltamivir) and rimantadine on the pharmacokinetics of Tamiflu
and rimantadine. Healthy volunteers will receive multiple oral doses of Tamiflu, rimantadine
or Tamiflu plus rimantadine in random order, with a minimum wash-out period of 7 days between
treatments. Anticipated time on study is up to 11 weeks.