A Pharmacokinetic and Pharmacodynamic Study of Phenoxymethylpenicillin for Children

• Status: Completed
• Trial end date: 2013-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this trial is to evaluate the pharmacokinetics and pharmacodynamics of penicillin V in non-infectious children to estimate the optimum dosage regime in children.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Aarhus
• Collaborators: Aarhus University Hospital Skejby; Department of Microbiological Surveillance and Research, SSI.
• Treatments: Penicillin V

Criteria

Inclusion Criteria:

• Non-infectious Danish children at age 0-10 years who were admitted for a chromium51EDTA clearance test

Exclusion Criteria:

• Children with allergy to penicillin and children with a prior known reduced glomerular filtration rate