Overview

A Phase 1/2 Study Evaluating the Safety and Efficacy of CLBS201 in Patients With Chronic Kidney Disease and Type 2 Diabetes Mellitus

Status:
Not yet recruiting
Trial end date:
2024-08-15
Target enrollment:
0
Participant gender:
All
Summary
CLBS201 will be studied to evaluate the safety, tolerability, and therapeutic effect in subjects with CKD and Type 2 DM.
Phase:
Phase 1/Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Caladrius Biosciences, Inc.
Criteria
Inclusion Criteria:

1. Adults aged 18 to 75 years

2. Documented diagnosis of type 2 diabetes

3. eGFR of 30 to <45 mL/min/1.73m at the screening visit.

4. UACR 300 mg/g to ≤ 5000 mg/g

Exclusion Criteria:

1. Hemoglobin < 10 g/dL

2. Hemoglobin A1c ≥8% at the time of screening

3. Acute kidney injury within 6 months prior to screening