A Phase 1 Positron Emission Tomography Study to Measure Cholesterol 24S-Hydroxylase Target Occupancy of TAK-935
Status:
Completed
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the brain cholesterol 24S-hydroxylase (CH24H)
enzyme occupancy of TAK-935 after single oral dose in healthy participants using the positron
emission tomography (PET) ligand [18F]MNI-792 and PET imaging and to determine the
relationship of occupancy to TAK-935 exposure.