Overview

A Phase 1b/2a Study Evaluating AMG 232 in Metastatic Melanoma

Status:
Completed
Trial end date:
2018-12-27
Target enrollment:
Participant gender:
Summary
Phase 1b/2a, open-label, sequential dose escalation and expansion study of AMG 232 in combination with trametinib and dabrafenib in subjects with metastatic melanoma followed by a direct comparison of AMG 232 combined with trametinib and dabrafenib versus trametinib combined with dabrafenib alone.
Phase:
Phase 1
Details
Lead Sponsor:
Amgen
Kartos Therapeutics, Inc.
Collaborator:
GlaxoSmithKline
Treatments:
Dabrafenib
Trametinib