Overview A Phase 1b Study Evaluating AMG 232 Alone and in Combination With Trametinib in Acute Myeloid Leukemia Status: Completed Trial end date: 2017-07-31 Target enrollment: Participant gender: Summary Open-label, sequential dose escalation and expansion study of AMG 232 in subjects with acute myeloid leukemia. Phase: Phase 1 Details Lead Sponsor: AmgenKartos Therapeutics, Inc.Treatments: Trametinib