Overview

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

Status:
Recruiting
Trial end date:
2025-03-01
Target enrollment:
Participant gender:
Summary
ATRC-101-A01 is a Phase 1b, open-label dose escalation trial of ATRC-101, an engineered fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a naturally occurring human antibody. The safety, tolerability, PK, and biological activity of ATRC-101 will be characterized when administered every two weeks (Q2W) or every 3 weeks (Q3W) as a monotherapy or in combination with other anticancer agents.
Phase:
Phase 1
Details
Lead Sponsor:
Atreca, Inc.
Treatments:
Doxorubicin
Liposomal doxorubicin
Pembrolizumab