Overview

A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors

Status:
Recruiting
Trial end date:
2022-05-01
Target enrollment:
Participant gender:
Summary
Assessment of the efficacy and safety of Regorafenib and Avelumab in patients with advanced or metastatic solid tumors (ten cohorts), once the Recommanded Phase II Dose (RP2D) has been determined (phase I trial). Assessement of the efficacy and safety of a low-dose of regorafenib (80mg/day) with avelumab in patients with advanced or metastatic colorectal tumors.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Institut BergoniƩ
Collaborators:
Bayer
Merck KGaA
Merck KGaA, Darmstadt, Germany
Treatments:
Antibodies, Monoclonal
Avelumab