Overview

A Phase I Study of Oral ABL001 in Patients With CML or Ph+ ALL

Status:
Active, not recruiting
Trial end date:
2024-03-14
Target enrollment:
Participant gender:
Summary
The design of a phase I, open label, dose finding study was chosen in order to establish a safe and tolerated dose of single agent ABL001 in CML and Ph+ ALL patients who are relapsed or refractory to or are intolerant of TKIs, and of ABL001+Nilotinib, ABL001+Imatinib and ABL001+Dasatinib in Ph positive CML patients who are relapsed or refractory to TKIs.
Phase:
Phase 1
Details
Lead Sponsor:
Novartis Pharmaceuticals
Treatments:
Dasatinib
Imatinib Mesylate
Niacinamide