A Phase I Trial to Assess the Effects of Food and Formulation on PK of KPT-330 in Patients With Sarcoma
Status:
Completed
Trial end date:
2016-11-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to find out more information such as: to determine the
effects of high and low fat foods on the pharmacokinetics (PK) of oral KPT-330 tablets, to
compare PK of capsules and tablets, to assess the effects of KPT-330 on cellular morphology
and biomarker changes on sarcoma biopsy specimens (in patients who can safely undergo
biopsy).